The economic impact of the global pandemic, especially in developing countries, has created significant challenges. Many sectors experienced sharp declines, including tourism, trade and investment. The tourism sector, which many developing countries rely on, has been hit hard by border closures and travel restrictions. For example, countries such as Indonesia and Thailand, which depend on international tourists, face billions of dollars in losses. The closure of hotels and restaurants led to a large increase in unemployment, increasing economic instability. Global trade is also hampered. Developing countries that rely on commodity exports, such as coffee, cocoa and palm oil, are experiencing a decline in demand from developed countries. In many cases, supply chains are disrupted, increasing production costs and inflation. Many small manufacturers have been hit hard, struggling to survive without adequate financial support. Foreign direct investment (FDI) in developing countries also declined. Economic uncertainty and health risks reduce investor interest. Many development projects have had to be postponed or cancelled, which has the potential to slow long-term economic growth. FDI is an important source for infrastructure development and job creation. The health sector is also experiencing quite heavy pressure. Developing countries often lack the resources to deal with pandemics. Costs to the health system are increasing, while tax revenues are decreasing drastically. This created a significant budget deficit, forcing the government to take on debt and cut budgets in other important sectors, such as education and social protection. However, there are also some positive effects for developing countries. Digital technology and financial innovation are gaining momentum. Many businesses are turning to online models to survive. The increasing use of the internet and applications for digital transactions shows the potential for growth in this sector. Society is increasingly adapting to technology, which can help increase economic efficiency in the future. Furthermore, this crisis has accelerated awareness of the importance of sustainability. Efforts to develop a greener and more inclusive economy are gaining attention. Initiatives for investment in renewable energy and sustainable infrastructure are starting to gain support. Governments and NGOs collaborate to create programs that encourage economic recovery while prioritizing environmental responsibility. Macroeconomic policy is very important in dealing with this impact. Developing countries must formulate stimulus strategies to support struggling sectors. Some countries, such as Brazil and South Africa, have introduced stimulus packages that include cash assistance for people experiencing hardship. International cooperation is also very necessary. Support from multilateral institutions, such as the IMF and World Bank, is key to helping developing countries deal with the crisis. Cheap loans and grants can provide room for governments to reinvest in their economies. Social resilience must also be improved. Social protection programs must be expanded to reach the most vulnerable in society. Through subsidy or direct assistance programs, the state can reduce the negative impact of job loss. Ultimately, while the global pandemic poses many challenges for developing countries, there are opportunities emerging amidst the adversity. With the right policies, innovation, and global cooperation, these countries can rebuild their economies in a more inclusive and sustainable way.